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New Hope Research, Forge Biologics Enter cGMP Manufacturing Pact

The Foundation will leverage Forge’s platform processes, including its HEK293 suspension Ignition Cells.

The New Hope Research Foundation, a nonprofit organization dedicated to finding a genetic cure for GM2 gangliosidosis (including Tay-Sachs disease) and other lysosomal storage diseases, and Forge Biologics, a manufacturer of genetic medicines, entered into a development and cGMP manufacturing partnership to advance the Foundation’s novel gene therapy, NHR01, into Phase I/II clinical trials for patients with GM2 gangliosidosis. Forge will provide adeno-associated virus (AAV) process developmen...

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